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KMID : 0191120210360360246
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Journal of Korean Medical Science
2021 Volume.36 No. 36 p.246 ~ p.246
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Latent Tuberculosis Infection Screening and Treatment in Congregate Settings (TB FREE COREA): Demographic Profiles of Interferon-Gamma Release Assay Cohort
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Kim Hyung-Woo
Min Jin-Soo
Choi Joon-Young
Shin Ah-Young
Myong Jun-Pyo
Lee Yun-Hee
Yim Hyeon-Woo
Jeong Hyun-Suk
Bae Sang-Hyuk
Shim Eun-Hye
In Hye-Kyung
Chun Chae-Min
Kim Ga-Hee
Kang Ji-Young
Lee Sung-Soon
Park Jae-Seuk
Kim Ju-Sang
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Abstract
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In 2017, the Korean government launched an unprecedentedly large-scaled latent tuberculosis infection (LTBI) screening project which covered more than a million individuals in congregate settings. A total of 1,047,689 participants of source population (n = 2,336,157) underwent LTBI testing from 2017 to 2018. The overall LTBI test uptake rate during this project was 44.8%. Workers in daycare centers (83.5%) and kindergartens (78.9%) showed high participation rate. A total of 1,012,206 individuals with valid results of interferon-gamma release assay (IGRA) were selected to constitute the IGRA cohort. Most of the enrolled participants in the IGRA cohort were in their working age. Approximately, three-quarters of total enrolled population were female. Investigating the LTBI prevalence, stages of LTBI care cascade, natural history of LTBI, efficacy of LTBI treatment and cost-effectiveness of LTBI screening are feasible within this IGRA cohort.
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KEYWORD
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Latent Tuberculosis, Interferon-gamma Release Tests, Republic of Korea, Mass Screening
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